Magnetic Bead Stirrer

     


  Magnetic Bead Stirrer for 8 Channel Pippettors

     
 


VP 767-4 & VP 758-3

     
 


In order to stir magnetic beads you can not use any method that employs magnetism, magnetic drives or magnetic clutches because the beads will be attracted to them and taken out of solution.  As magnetic beads have become more popular in a variety of assays, a non-magnetic method to keep them uniformly  suspended is required. It is also important to use a method and reservoir that does not have "fall out zones" places where the bead fall out of solution.  The "fall out zone" problem is a difficult one for those stirrers that use a propeller blade approach as the corners of those reservoirs are "fall out dead zones".   Similar problems are found in the corners of mixers that use ultrasound to mix beads.

The VP 767-4  and VP 758-3 with its' sealed drive shaft eliminates the need for magnetic clutches or drive magnets and the design of the Bubble Paddle Reservoir takes care of the "fall out zone".  Problem solved!  The pipet depressions on the bottom of the reservoir also reduces the waste of these precious reagents.

The reservoirs come standard in;
economical Delrin (VP 758-3)
in autoclaveable Polypropylene (VP 758-3P) and in autoclaveable PTFE (VP 758-3PTFE)

Over all Reservoir Specifications:
109 mm long, 51 mm wide, 42 mm tall
Reservoir depth = 32 mm**
Reservoir volume = 50 ml
Dead volume = 3 ml

Over all Reservoir and Motor Specifications:
284 mm long, 78 mm wide and 72 mm tall.

The sealed drive shaft is subject to wear.  The degree of wear is determined by the material being stirred and the length of the stirring time.   The seal should not be operated dry.  Although you will get hundreds of hours of operation before the seal fails we have provided a simple replacement sealed drive shaft (VP 758-3S).  This  unit is simple enough that it can be replaced in the field so there is no down time.  The photo above illustrates the double O-rings used to attach the unit to the reservoir.  The photo to the right illustrates the custom Bal Seal used to seal the drive shaft.  The unit also contains 2 bearings to keep the shaft true and reduce wear on the Bal Seal.  

 

 
 


The photo to the right shows the Magnetic Stirrer being used on an Apricot Designs TPS-384 robot.

Download Video
(mpeg movie- 4MB)

 

Press the play button to view the video in a flash format, flash must be installed, or click the download link to download a mpeg version.

 
 
 


Viscous Liquid Mixer

     
  In addition to mixing magnetic beads the direct drive sealed bearing Bubble Paddle Stirrers are also good at stirring very viscous liquid.
 
     
 

 
  Technical Documents:
    Magnetic Bead Bubble Paddle Stirrer Manual

  Videos:
    Magnetic Bead Stirrer in action
 

 



Large Volume Magnetic Bead Stirrers
VP 758-3MAX & VP 767-2MAX

     
 

The VP 758-3MAX & VP 767-2-MAX Magnetic Bead Stirrer was made for a customer who needed to keep 400 ml of magnetic beads in solution while pipetting them into 96 well assay plates on a Tecan work station.  Our solution was to make a 450 ml reservoir with 13 bubble paddle blade.
 


Download video of Bead Stirrer in action
(mpeg movie- 18MB)


Press the play button to view the video in a flash format, flash must be installed, or click the download link to download a mpeg version.

 

 


VP 758-4PP

     
 


Improved polypropylene reservoir with ducted bottom for 8 pipettes including aluminum paddle with 9 bubbles and double sealed drive shaft. Mixes 125ml.

 
 
 
The photo to the right demonstrate the VP 767-2 with a VP 581A mounted on the bottom which allows it to be located in a standard SBS footprint.
 
 


VP 758-4PTFE

     
 


Improved PTFE reservoir with ducted bottom for 8 pipettes including aluminum paddle with 9 bubbles and double sealed drive shaft. Mixes 125ml.

 
 
     
 

VP 758-5PP & VP 767-3

     
 

The VP 758-5PP & VP 767-3 is another Magnetic Bead Stirring system for magnetic bead suspensions as high as 450 ml but with a shorter and wider Reservoir then the VP 7583MAX. The VP 758-5PP Reservoir is made of polypropylene and designed for 8 or 12 pipette tips. It has a ducted bottom and includes an aluminum paddle with 13 bubbles and a double sealed drive shaft.

 
 
 

In the photos to the right, the VP 758-5PP/VP 767-3 system is attached to two VP 581B Adapter Bases. These bases have SBS dimensions and provide easy mounting on robotic instruments decks.

 
 
   

 
  Technical Documents:
    CAD drawing of dimensions
 

     
 


VP 758-3S

     
 


Replacement seal bearing for VP 758-3, VP 758-3P Or VP 758-3PTFE, Includes shaft.

 
 



  Miniature Magnetic Bead Stirrer

     
 


The VP 767M  and VP 758M are miniature versions of the VP 767-2 and the VP 758-3.  They were designed to be compatible with the Innovadyne Nanodrop for magnetic bead dispensing.  The VP 758M uses a similar sealed drive shaft as the VP 758-3 and the bubble paddle and pipet depressions on the bottom of the reservoir are  identical to the VP 756CM-P thus combining the best of both worlds to produce uniform suspensions of magnetic beads with very low dead volumes.

Reservoirs come standard in autoclaveable Polypropylene (VP 758M) with an inlet and outlet nipple.

Over all Reservoir Specifications:
141 mm long, 23 mm wide, 23 mm tall
Reservoir depth = 16 mm
Reservoir volume = 15 ml
Dead volume = 1.2 ml

Over all Reservoir and Motor Specifications:
253 mm long, 27 mm wide and 26.2 mm tall.

 
 
 
The motor unit is also available in 230 volts 50hz and CE complaint for European customers as the VP 767M-CE.
 
 
 



  Magnetic Bead Stirrer for 96 Channel Pippetors

 
 


VP 769 / VP 759

     
 
In order to stir magnetic beads you can not use any method that employs magnetism, magnetic drives or magnetic clutches because the beads will be attracted to them and taken out of solution.  As magnetic beads have become more popular in a variety of assays, a non-magnetic method to keep them uniformly  suspended is required. It is also important to use a method and reservoir that does not have "fall out zones" places where the bead fall out of solution.  The "fall out zone" problem is a difficult one for those stirrers that use a propeller blade approach as the corners of those reservoirs are "fall out dead zones".   Similar problems are found in the corners of mixers that use ultrasound to mix beads.

The VP 769 and VP 759 with its' sealed drive shafts eliminates the need for magnetic clutches or drive magnets and the design of the Bubble Paddle Reservoir takes care of the "fall out zone".  Problem solved!  The pipet depressions on the bottom of the reservoir also reduces the waste of these precious reagents.

The reservoirs come standard in;
economical Delrin (VP 759) in autoclaveable Polypropylene (VP 759P) and in autoclaveable PTFE (VP 759PTFE)

The motor/drive systems are also available in a 230 volt 50 hz CE complaint version (VP 769CE).

 
 
 


Motor Gear Drive

     
 


The latest in our line magnetic bead stirrers is the VP 759 Bubble Paddle Reservoir and the VP 769 Motor/gear drive.  This system made for 96 robot pipetting systems is shown in the photo to the right on the deck of a PerkinElmer EP3.  This system is designed to fit on one of the corner positions.  The least impact on deck positions (one deck position) required is when the system is located on either the upper right hand corner or the lower left hand corner.  Two deck positions are required when it is placed in the lower right as illustrated in the photo or in the upper left.  Three deck positions are required if the installation is on an edge position.   

The photo to the right illustrates the motor and gear system of the VP 769 in its rotated up position.  We have designed the system so alignment pins (not shown) on the bottom of the base plate register with registration holes used on the EP3 to locate microplate tiles.    The base plate has two alignment pins which register and locate the VP 759 Bubble Paddle Reservoir so the pipetting points are the same as a 96 well microplate.  The adjustment screw in the lower right is for setting the degree of tooth engagement on the gears.    

Over all Reservoir Specifications:
 mm long,  mm wide,  mm
tall
Reservoir depth = mm**
Reservoir volume =  ml
Dead volume =  ml

Over all Reservoir and Motor Specifications:
 mm long,  mm wide and  mm tall.
 

 

 
 



  Programmable Smart Switch

     
 


A cost effective way to automate our Magnetic Bead Stirrer is to use our new Programmable Smart Switch VP 700.  Follow this link for more information.

 
 
   


Improved Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 8 pipet tips, includes 1  VP 758-3  sealed drive shaft Delrin reservoir, 1 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds 50 ml, the reservoir is 109 mm long, 51 mm wide, 42 mm tall, 32 mm deep.  Powered by a DC Brush motor with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are; 284 mm long, 78 mm wide and 72 mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 767-2).
 

  VP 767-2 & VP 758-3


Improved Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 8 pipet tips, includes 1 autoclaveable VP 758-3P  sealed drive shaft polypropylene reservoir, 1 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds 50 ml, the reservoir is 109 mm long, 51 mm wide, 42 mm tall, 32 mm deep.  Powered by a DC Brush motor with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are; 284 mm long, 78 mm wide and 72 mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 767-2).
 

  VP 767-2 & VP 758-3P


Improved Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 8 pipet tips, includes 1 autoclaveable VP 758-3PTFE  sealed drive shaft PTFE reservoir, 1 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds 50 ml, the reservoir is 109 mm long, 51 mm wide, 42 mm tall, 32 mm deep.  Powered by a DC Brush motor with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are; 284 mm long, 78 mm wide and 72 mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 767-2).
 

  VP 767-2 & VP 758-3PTFE

Replacement sealed drive shaft for VP 758-3
 
  VP 758-3S


Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 8 pipet tips, includes 1  VP 758M  sealed drive shaft polypropylene reservoir, 1 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds 10 ml, the reservoir is 141 mm long, 23 mm wide, 23 mm tall, __mm deep.  Powered by a DC Brush motor with a top speed of 1,000 RPM. The overall drive and reservoir dimensions are; 253 mm long, 27 mm wide and 26.2 mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 767M).
 

  VP 767M & VP 758M


Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 96 pipet tips, includes 1  VP 759 with 4 sealed drive shafts in a Delrin reservoir, 4 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds    ml, the reservoir is    mm long,    mm wide,    mm tall, 32 mm deep.  Powered by a DC Brush motor with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are;    mm long,    mm wide and    mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 769).
 

  VP 769 & VP 759


Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 96 pipet tips, includes 1  VP 759 with 4 sealed drive shafts in a polypropylene reservoir, 4 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds    ml, the reservoir is    mm long,    mm wide,    mm tall, 32 mm deep.  Powered by a DC Brush motor with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are;    mm long,    mm wide and    mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 769).
 

  VP 769 & VP 759P

Direct Drive Replaceable seal drive shaft Bubble Paddle Reservoir for 96 pipet tips, includes 1  VP 759 with 4 sealed drive shafts in a PTFE reservoir, 4 VP Parylene coated Aluminum Bubble Paddle (9 bubbles each), holds    ml, the reservoir is    mm long,    mm wide,    mm tall, 32 mm deep.  Powered by a DC Brush motor with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are;    mm long,    mm wide and    mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 120 volts (VP 769).
 

  VP 769 & VP 759PTFE
   
CE marked motors/power supplies for sale to Europe

CE mark DC Brush motor and housing with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are; 284 mm long, 78 mm wide and 72 mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 230 volts.  Use with VP 758-3, VP 758-3P or VP 758-3PTFE
 

  VP 767-2CE

CE mark DC Brush motor and housing with a top speed of 1,000 RPM. The overall drive and reservoir dimensions are; 253 mm long, 27 mm wide and 26.2 mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 230 volts.  Use with VP 758M

  VP 767M-CE

CE mark DC Brush motor and housing with a top speed of 3,000 RPM. The overall drive and reservoir dimensions are; mm long,  mm wide and  mm tall.  Also includes a variable 24 volt DC Power Supply which operates off 230 volts.  Use with VP 759, VP 759P or VP 759PTFE

  VP 769-CE
 
         

 

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