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Several of our customers wanted to heat as they stirred their
samples. The commercially available heating blocks are not compatible with
magnetic stirring because they position the samples too far above the stir deck
or they contain ferrite elements that block the magnetic flux. We have
built robust heating blocks that have a very low profile with no ferrite
materials. This design minimizes the distance from the samples to the
magnetic drive thus maximizing the stirring power.
Another advantage of our design is that we have separated the
control panel from the actual heating block. Thus the heating block is
very small and easily fits into areas where space is at a premium, like the deck
of a robotic workstation.
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The VP 743 Block Heater is constructed of anodized
aluminum and has a lid that can be screwed into place to seal cap matts onto
deep well microplates. It is used to heat three deep well microplates
or 3 racks of glass vials from 25C to 100C.
The temperature is determined +/- 1C by a Watlow controller and a thermocouple. It
requires 115 volts at 4 amps to power a 450 watt heater. It will bring water to a boil in 45
minutes and up to 80C in 20 minutes. The outside dimensions of the block
are 49.5 cm long by 11.2 cm wide and 5.4 cm tall. With the lid in
place it is 6.1 cm tall. The three cavities of the heat block are
separated by an aluminum web. Each cavity is 12.8 cm long, 8.6 cm
wide and 3.5 cm deep. The bottom of the wells or vials are only 1.9
cm above the stir deck for maximum magnetic coupling. The VP 743 was
designed to be used with the VP 710E-2 series Alligator Tumble Stirrers.
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The figure to the right represents the difference in temperature with time
for various well locations in a microplate. Although each location
has different exposure to the heating block all three locations are within
3C of each other after 40 minutes.
An additional use for the Heating Blocks is in
conjunction with our
evaporation
manifolds to aid in the evaporation of solvents from microplates or
test tubes.
We make heating blocks to fit your application.
Contact us with your needs.
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Designed to meet the
high temperature requirements of chemists to heat and stir reactions the VP 741A Block Heater is constructed
of anodized aluminum and has a lid that can be screwed into place to seal cap matts onto
deep well microplates. It is insulated with Millboard on the bottom to protect both the
Tumble Stirrer deck and personnel. It is used to heat one rack of glass vials from 25C to
200C.
The temperature is determined +/- 1C by a Watlow controller and a thermocouple.
It requires 115 volts at 7 amps to power two cartridge heaters. It will
bring water to a boil in 3 minutes and the block up to 200C in
6 minutes.
The outside dimensions of the block are 16 cm long by 10.6 cm wide and 5.4 cm
tall. With the lid in place it is 6.1 cm tall. The cavity of the
heat block is 12.8 cm long, 8.6 cm wide and 3.5 cm deep. The bottom of
the wells or vials are only 1.9 cm above the stir deck for maximum magnetic
coupling. The VP 741A when operated at 50C or less can be used
with any of the VP 710 series Alligator
Tumble Stirrers. At temperatures from 50C to 200C we suggest you use
the VP 710GHHT Tumble Stirrer which has a mating feature for the VP 741A.
Because thermocouples are sensitive to high speed rotating
magnetic fields we do not recommend stirring at speeds
higher than 100 RPM.
If you need to stir at
speeds greater than 100 RPM we suggest you used the RTD
temperature sensing device available with the VP 741A-R.
The only difference between the VP 741A (thermocouple) and
the VP 741A-R (RTD) is the temperature sensing devices.
RTD's are not affected by moving magnetic fields.
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The VP 741A can also be mated to a
VP 581B-MICA to allow
the heat block to be registered on a robot deck so the plate
wells will be at the same position as on a plate deck tile.
The Muscovite Mica is also a good
insulator and a way to prevent or reduce heat from the heat
block transferring to the robot deck. The
Muscovite Mica is safety rated by UL laboratories as UL
94VO. |
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Originally designed to meet the
high temperature requirements of scientists to heat PCR plates on a
robot
deck. The "cut away" low profile design allows the robot plate handler
to move the PCR plates around the deck between multiple VP 741BW-MICA
heating
stations and cooling stations. We have recently
improved the VP 741BW by replacing the polypropylene registration block (VP
581A) with a Muscovite Mica registration block
(VP 581B-MICA). This
solves a problem with the polypropylene registration block expanding at
temperatures above 100C. The new heat block is called the VP
741BW-MICA.
The VP 741BW-MICA can accommodate a PCR insert
(VP 741I6) the VP 741BW-MICA Block Heater is constructed of anodized
aluminum. It is insulated on the bottom with a Muscovite
Mica registration
block (VP
581B-MICA) to register the VP 741BW-MICA to the deck and also to prevent
the deck from heating up. It is used to heat one microplate plate from 25C to
200C. Not only is the Muscovite Mica a good insulator
it is also thermally stable and does not expand or shrink with heat and
cold.
Recently ProMega has incorporated the VP
741BW heat block as a central element in their new
DNA IQTM
Forensic assay that they process
on the new Beckman 3000 workstation.
The temperature is determined +/- 1C by a Watlow SD series controller and a
thermocouple. It requires 115 volts at 7 amps to power two cartridge heaters.
It will bring water to a boil in 3 minutes and the block up to 200C in
6
minutes. The outside dimensions of the block are 18.1 cm long by 10.6 cm
wide and 5.4 cm tall. With the VP 581B-MICA in place it is 7.0 cm tall.
The cavity of the heat block is 12.8 cm long, 8.6 cm wide and 0.6 cm deep.
Promega has
published the efficacy and
uniformity of heating with the VP 741BW.
The VP 741BW-MICA is also available in a 230 volt version that
is CE complaint (VP 741BWCE-MICA).
Heating and Stirring
For use of the heating blocks on our Magnetic Tumble
Stirrers we recommend that you use the VP 741BW-R-MICA
which uses a RTD
probe to determine the temperature instead of the thermocouple used in the
VP 741BW-MICA. (Thermocouples are not affected by slowly rotating magnetic
fields (< 100RPM) but they are affected by faster speeds. The price is
the same for both heating blocks. The VP 741BW-R-MICA is also available in a 230 volt version that
is CE complaint (VP 741BW-RCE-MICA).
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The VP 741BW-MICA connects to the computer through RS-485 or RS-232
with included converter. |
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The VP 743A-1RM replaces the VP 743A with its
Mica insulation.
Instead of insulating the heating block we attach Mica insulation to the VP
710E-2HM. The VP 743A-1RM
uses three Mica
insulation blocks
to attach to the VP 710E-2HM
Tumble Stirrer deck to protect it from the 200C heat.
The VP 743A-1RM uses an RTD probe to
determine the temperature. RTD probes are not
sensitive to magnetic field sweeps and therefore are
preferable for magnetic stirring operations.
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The three Mica insulation blocks on the
bottom of the VP 743A-1RM.
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The VP 743A-1RM is used to heat three
polypropylene microplates or racks of glass vials from 25C to 200C. The
temperature is determined +/- 1C by a Watlow controller and a thermocouple. It
requires 115 volts at 4.6 amps to power four cartridge heaters. It will
bring water to a boil in 8 minutes and the block up to 200C in
15 minutes.
The outside dimensions of the block including the insulation are 60.7cm long
by 12.4 cm wide and 6.6 cm tall. With the lid in place it is 7.3 cm tall.
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The three cavities of the heat block are
separated by an aluminum web. Each cavity is 12.8 cm long, 8.6 cm
wide and 3.5 cm deep. The bottom of the wells or vials are only 2.4
cm above the stir deck for maximum magnetic coupling. The VP 743A-1RM was
designed to be used with the VP 710E-2HM series Alligator Tumble Stirrers.
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Designed to meet the
high temperature requirements of chemists to heat and stir reactions the VP 743A-1RM Block Heater is constructed
of anodized aluminum and has a lid that can be screwed into place to seal cap matts
onto deep well microplates.
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Download Video
(mpeg movie- 12MB)
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Download Video
(mpeg movie- 11MB)
Press
the play button to view the video in a flash format, flash must
be installed, or click the download link to download a mpeg
version. |
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One of our customers wanted to get the fastest heat
transfer from our VP 741, VP 743 and VP 743A heating blocks to the wells of his deep
well microplate without using a messy liquid heat conductor. Because
most deep well microplates have a "skirt" around them, it is like having a
built in air insulator that prevents heat transfer. The
AbGene #AB-0661 with its 2.2 ml volume
and NO skirt offers a way to solve this problem. We developed a
5 piece aluminum heat insert (VP 741-I) to surround the AB-0661
plate and with the VP 741 lid, completely enclose it. The bottom
plate is machined in a sculpted fashion to closely follow the outside
contours of the plate bottom. The bottom piece fits so tight it
has to be pried off with a screwdriver. The sides and end sections are
held tight to the outside walls with a rubber band.
This is a simple yet very effective solution to enhance
heat transfer.
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The VP 741I6B is our newest aluminum heat transfer base. It was designed
specifically for the AbGene (#ab093) 96 deep well microplate. It features an sbs
footprint and is sculpted to closely follow the outside contours of the plate
bottom. It can be used on VP 741BW-R or on commercially available dry bath
heating units. Contact one of our sales staff if you require a heat transfer
base for your specific plate type.
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The VP 741I6A heating block insert is ideal for use
with the VP 741B heating block. With the "cut away" design it provides
easy access for robotic plate handlers. Made from anodized aluminum
with conical holes to match the topography of the PCR plate it provides a
very efficient transfer of heat from the heating block to the PCR
plate.
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The VP 416-ALB-20 is a heat block insert that fits inside
our standard VP 741 through VP 744 Heat Block series. It
has a special design which minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat.
The
heat block insert has 20 flat bottom wells with each being 17 mm wide by
20.7 mm deep.
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The vial used in the
photos to the right is a
2dram vial with the dimensions
16.6 x 60 mm.
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The photo to the right also shows a
VP 416-ALB-LID and
a foam silicone rubber gasket attached
to the block to provide a cover for the vials.
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The VP 416-ALB-24 is a heat block insert that fits inside
our standard VP 741 through VP 744 Heat Block series. It
has a special design which minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat.
The
heat block insert has 24 flat
bottom wells with each
being
15.1 mm wide by
20.7 mm deep.
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The vial used in the
photos to the right is a 1dram vial with the dimensions
15 x 45 mm.
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer. It also shows a
VP 416-ALB-LID and
a foam silicone rubber gasket attached
to the insert to provide a cover for the vials. |
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The VP 416-ALB-30 is a heat block insert that fits inside
our standard VP 741 through VP 744 Heat Block series. It
has a special design which minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat.
The heat block insert
has 30 wells shaped to accommodate microcentrifuge
tubes.
Each well bottom has a conical shape to conform to microcentrifuge tubes and is
11 mm wide by 23.5 mm deep.
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer.
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The VP 416-ALB-48 is a heat block
insert that fits inside our standard VP 741 through VP 744
Heat Block series. It has a special design which minimizes
the eddy current phenomena resulting from magnetic lines of
flux passing through large masses of aluminum without
affecting the insert’s ability to transfer heat.
The heat block insert has 48 round bottom wells
with each being 12 mm wide by
20.7 mm deep. |
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The photo to the right shows an assortment of vials, tubes,
and bottles that the
VP 416-ALB-48 will accommodate.
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer. It also shows a
VP 416-ALB-LID and
a foam silicone rubber gasket attached
to the insert to provide a cover for the vials.
The tubes used are 5 mL round bottom tubes with the dimensions
of 12 x 75 mm. |
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The VP 416-ALB-96 is a heat block insert that fits inside
our standard VP 741 through VP 744 Heat Block series. It
has a special design which minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat.
The heat block insert has 96 flat bottom
wells with each
being 8.6 mm wide by
21.7 mm deep. |
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The vials shown in the photos to the
right have the following dimensions:
8 mm wide x 30 mm tall
for the shorter one and
8 mm wide x 43 mm tall
for the taller one |
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer. It also shows a
VP 416-ALB-LID and
a foam silicone rubber gasket attached
to the insert to provide a cover for the vials.
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The VP 416-ALB-LID and a foam silicone rubber gasket
will attach to any of the VP 416-ALB
products to provide a cover for the vials.
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The VP 744 is a
heater/chiller aluminum block with an SBS feature on the bottom so it can be
located on robot platform deck tile. Two hose barb nipples connect the
serpentine channels in the heater/chiller to a pump and a hot or cold fluid
bath. Alignment holes and or registration pins on the VP 744 allow
accessories (in this case a VP 531R-1AL aluminum reagent reservoir) to be held in the same relative position as the SBS
feature on the VP 744, thus facilitating locating the accessory relative to
the robot deck tile. If you already have hot or cold bath and a
peristaltic pump you have everything you need.
If you need a
peristaltic pump check out
VP 560. |
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The Photo to right
illustrates the serpentine heating/cooling channels. |
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The photo on the right
is a bottom view, illustrating the SBS foot print feature that registers the
heating block to most robot plate tiles.
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The photo on the right
illustrates a VP 531R-1AL on the heating/chilling block.
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VP 745 Heater/Chiller block for regulating the temperature of a VP
750 Bubble Paddle Stirrer. We designed this system to fit on the deck
of a Caliper Sciclone with a VP 710C1 under the deck to power the Bubble
Paddle Stirrer. Just attach to a heater/chiller bath and a pump.
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Aluminum microplate to keep liquid in
wells cool. |
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The VP 581C-AL was designed to keep the
contents of a microplate cool while on a robotic work
station. Made from block of solid aluminum 2.54 cm
thick the
VP 581C-AL will keep a microplate between 7C and
10C for over 15 minutes.
Follow this link to data showing the
ability of the VP 581C-AL to stabilize the temperature of a
96 well microplate with 300 ul of distilled water in each
well. The VP 581C-AL were either chilled to 7.8C or
-13C prior to placing on the robot deck. |
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Another more cost effective way to automate any of our
Heating Blocks is to use our new Programmable Smart Switch VP 700.
Follow
this link for more information.
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We also make custom inserts for heating blocks. The
one at the right was machined so the inside of the hole matched perfectly
with the round bottom of each of the different containers. The one
below incorporates various diameter holes and bottoms that conform very
closely with the outside surface of the glass bottles they hold. The
circular design facilitates stirring on a conventional horizontal magnetic
stirrer.
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