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Several of our customers wanted to heat as they stirred their
samples. The commercially available heating blocks are not compatible with
magnetic stirring because they position the samples too far above the stir deck
or they contain ferrite elements that block the magnetic flux. We have
built robust heating blocks that have a very low profile with no ferrite
materials. This design minimizes the distance from the samples to the
magnetic drive thus maximizing the stirring power.
Another advantage of our design is that we have separated the
control panel from the actual heating block. Thus the heating block is
very small and easily fits into areas where space is at a premium, like the deck
of a robotic workstation.
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The VP 743 Block Heater is constructed of anodized
aluminum and has a lid that can be screwed into place to seal cap matts onto
deep well microplates. It is used to heat three deep well microplates
or 3 racks of glass vials from 25C to 100C.
The temperature is determined +/- 1C by a Watlow controller and a thermocouple. It
requires 115 volts at 4 amps to power a 450 watt heater. It will bring water to a boil in 45
minutes and up to 80C in 20 minutes. The outside dimensions of the block
are 49.5 cm long by 11.2 cm wide and 5.4 cm tall. With the lid in
place it is 6.1 cm tall. The three cavities of the heat block are
separated by an aluminum web. Each cavity is 12.8 cm long, 8.6 cm
wide and 3.5 cm deep. The bottom of the wells or vials are only 1.9
cm above the stir deck for maximum magnetic coupling. The VP 743 was
designed to be used with the VP 710E-2 series Alligator Tumble Stirrers.
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The figure to the right represents the difference in temperature with time
for various well locations in a microplate. Although each location
has different exposure to the heating block all three locations are within
3C of each other after 40 minutes.
An additional use for the Heating Blocks is in
conjunction with our
evaporation
manifolds to aid in the evaporation of solvents from microplates or
test tubes.
We make heating blocks to fit your application.
Contact us with your needs.
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The VP 741AW-R-MB Heating Block provides more consistent heating (+/- 1°C) than standard heat blocks, allows heating to high
temperatures (up to 200°C), and can be combined with stirring using one of V&P’s Tumble Stirrers. This Heating Block is constructed of
anodized aluminum and has a deep chamber and lid that can be screwed into place to reach high temperatures and hold CapMats or other sealing
materials in place. The Heating Block comes with a U-shaped insert that allows easy removal of standard microplates or other short labware. It also includes
an SBS Adaptor Base made of 12.5 mm thick Mica that is attached to the Heating Block’s underside. This Base provides heat protection for surfaces below
the Heating Block and facilitates its use on SBS-configured locations such as
V&P Stirrers or robotic decks. The Mica is safety rated by UL laboratories as UL 94VO.
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The VP 741AW-R-MB can be used to heat standard microplates, deepwell plates, PCR plates, or SBS-sized racks of tubes or vials
from 25°C to 200°C. Temperature is controlled by a Watlow PID controller that uses an RTD (Resistive Thermal Device) heat sensor. RTD sensors
are advantageous because they are not affected by the moving magnetic fields generated by V&P Tumble Stirrers. This becomes important when heating
and stirring simultaneously (see below).
- Outside dimensions: 18.1 cm length x 10.5 cm width x 6.8 cm height.
- Height with lid in place: 7.42 cm
- Dimensions of heating chamber: 12.8 cm height x 8.6 cm width x 3.5 cm depth
If stirring at the same time on one of our Tumble Stirrers, the bottoms
of the wells, tubes or vials are only 1.9 cm above the stir deck for maximum magnetic coupling. If heating above 100C on a Tumble Stirrer, it is
recommended that the Stirrer also be Mica heat-protected, for example, see VP
710E-2HM-1
This Heating Block is available in a 230 volt version that is CE compliant (VP 741AW-RCE-MB).
Both versions above can be made with a slightly thicker SBS Adaptor Base of 18.75 mm thickness (VP 741AW-R-MA and VP 741AW-RCE-MA) for situations in
which the Heating Block needs to be raised, for example, with certain robotic plate nests. |
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The VP 741ABW-R-MB is specially designed for use in combination heating and stirring. The design minimizes drag on the
Tumble Stirrer motor due to Eddy currents given off by the changing magnetic field. This allows a broader range of V&P’s Stirrers, including
those with less powerful motors, to be used in combination with heating.
Click here to see how the
VP 741ABW-R-MB Heating Block is used on a VP 710E-2HM-1 Tumble Stirrer. Note that the SBS Mica insulating Adaptor Bases attached to the
undersides of the Heating Blocks fit nicely into the SBS Mica pockets on our Tumble Stirrers.
This Heating Block is also available in a 230 volt version that is CE compliant (VP 741ABW-RCE-MB). In addition, these versions can
be made with a slightly thicker SBS Adaptor Base of 18.75 mm thickness (VP 741ABW-R-MA and VP 741ABW-RCE-MA) for situations in which the Heating Block
needs to be raised, for example, with certain robotic plate nests.
Several of our Heating Blocks, including the VP 741ABW-R-MB, have been made with features that allow computer control of the temperature variables.
We are currently updating our computer control system and will post the features when available. However, if you are interested at any time, please contact
V&P Scientific technical personnel by phone or email (sales@vp-scientific.com). |
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The VP 741AJ is a polycarbonate shell that fits around our VP 741A series heat blocks to protect laboratory personnel from the hot Heating Block.
The shell can be used with temperatures up to 120°C.
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The VP 741BW-R-MB Heating Block has a shallow chamber ”cut away design” so that a robotic plate handler can move PCR plates and other microplates
around the deck. Like the “deep chamber” version described above, this Heating Block provides more consistent heating (+/- 1°C) than standard heat blocks, allows
heating to high temperatures (up to 200°C), and can be combined with stirring using one of V&P’s Tumble Stirrers. It is constructed of anodized aluminum.
One increasingly popular use of the VP 741BW-R-MB Heating Block is in protocols involving PCR plates, for example, DNA extraction from samples, DNA cleanup
after reactions, and sizing for NextGen Sequencing. The Heating Block comes with an SBS Adaptor Base made of 12.5 mm thick Mica that is attached to the Heating Block’s underside.
This Base provides heat protection for surfaces below the Heating Block and facilitates its use on SBS-configured locations such as V&P Stirrers or robotic decks. The Mica is
safety rated by UL laboratories as UL 94VO.
The VP 741BW-R-MB can be used to heat standard microplates, PCR plates, deepwell plates or SBS-sized racks of tubes or vials from 25°C to 200°C. Temperature is
controlled by a Watlow PID controller that uses an RTD (Resistive Thermal Device) heat sensor. RTD sensors are advantageous because they are not affected by the moving magnetic
fields generated by V&P Tumble Stirrers. This becomes important when heating and stirring simultaneously (see below).
- Outside dimensions: 18.1 cm length x 10.6 cm width x 5.4 cm height
- Dimensions of heating chamber: 12.8 cm length x 8.6 cm width x 0.6 cm depth
Heating of PCR plates or racks of tubes is greatly facilitated using V&P’s Heating Inserts such as the VP 741I6A
for 96-well PCR plates or the VP 416-ALB-48 for 12 mm diameter tubes or vials. We provide a variety of
Heating Inserts for various microplates and tubes to accelerate and maintain heated temperatures, and we customize Heating Inserts as needed.
If stirring at the same time on one of our Tumble Stirrers, the bottoms of the wells, tubes
or vials are only 1.9 cm above the stir deck for maximum magnetic coupling. If heating above 100C on a Tumble Stirrer, it is recommended that the Stirrer also be Mica heat-protected,
for example, see VP 710SM4PH
This Heating Block is available in a 230 volt version that is CE compliant VP 741BW-RCE-MB. In addition, both versions above can be made with a slightly
thicker SBS Adaptor Base of 18.75 mm thickness VP 741BW-R-MA and VP 741BW-RCE-MA for situations in which the Heating Block needs to be raised, for example, with certain robotic
plate nests.
Promega has incorporated one of our VP 741B version Heating Blocks as an important component in their DNA IQTM Forensic Assay.
In this article, they show that the efficacy and uniformity of heating with the VP 741B version Heating Block is excellent.
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The VP 741BBW-R-MB is specially designed for use in combination heating and stirring. The design minimizes drag on the Tumble Stirrer motor
due to Eddy currents given off by the changing magnetic field. This allows a broader range of V&P’s Stirrers, including those with less powerful motors, to be
used in combination with heating.
Click here to see how the VP 741BBW-R-MB
Heating Block is used on a VP 710SM4PH Tumble Stirrer. Note that the SBS Mica insulating Adaptor Bases attached to the undersides of the Heating Blocks fit nicely into the SBS
Mica pockets on our Tumble Stirrers.
This Heating Block is also available in a 230 volt version that is CE compliant, VP 741BBW-RCE-MB. In addition, these versions can be made with a slightly
thicker SBS Adaptor Base of 18.75 mm thickness (VP 741BBW-R-MA and VP 741BBW-RCE-MA) for situations in which the Heating Block needs to be raised, for example, with certain robotic
plate nests.
All Heating Blocks listed above can be made with features that allow computer control of the temperature variables. We are currently updating our computer
control system and will post the features when available. However, if you are interested at any time, please contact V&P Scientific technical personnel by phone or
email (sales@vp-scientific.com).
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The VP
741BW-MICA was built with a RS 485 computer connection on the Watlow control
. All temperature variables can be controlled via computer.
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The VP 741BW-MICA connects to the computer through RS-485 or RS-232
with included converter. |
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The VP 743AW-R-MB-1 replaces the VP 743A with its Mica insulation. Instead of just insulating the heating block we attach Mica insulation to the VP 710E-2HM Tumble Stirrer
deck to protect it from the 200C heat. The VP 743AW-R-MB-1 uses three Mica insulation blocks to position on the VP 710E-2HM Tumble Stirrer.
The VP 743A-1RM uses an RTD probe to determine the temperature. RTD probes are not sensitive to magnetic field sweeps and therefore are preferable for magnetic stirring operations. |
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The three Mica insulation blocks on the bottom of the VP 743AW-R-MB-1 heat block. |
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The VP 743AW-R-MB-1 is used to heat three polypropylene microplates or racks of glass vials from 25C to 200C. The temperature is determined +/- 1C by a Watlow controller
and a RTD temperature sensor. It requires 115 volts at 4.6 amps to power four cartridge heaters. It will bring water to a boil in 8 minutes and the block up to 200C in 15 minutes. The outside
dimensions of the block including the insulation are 60.7cm long by 12.4 cm wide and 6.6 cm tall. With the lid in place it is 7.3 cm tall. |
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The three cavities of the VP 743AW-R-MB-1 heat block are separated by an aluminum web. Each cavity is 12.8 cm long, 8.6 cm wide and 3.5 cm deep. The bottom of the wells or vials
are only 2.4 cm above the stir deck for maximum magnetic coupling. The VP 743AW-R-MB-1 was designed to be used with the VP 710E-2HM series Alligator Tumble Stirrer. |
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Designed to meet the high temperature requirements of chemists to heat and stir reactions the VP 743AW-R-MB-1 heat block is constructed of anodized aluminum and has a lid that can
be screwed into place to seal cap mats onto deep well microplates.
The VP 743AW-R-MB-1 is also available in a 230 volt version that is CE complaint (VP 743AW-R-MB-1CE). |
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The VP 741A-RM-B was designed to minimize Eddy Current
drag. The advantage is that either cheaper motors can be
used to spin the magnetic cylinders or that the motors will
last longer because the load will be less.
The photo to right
illustrates a VP 741A-RM-B on VP
710E-2HM-1. |
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The photo on the right illustrates the MICA heat resistant
(shielding) bottom. We have found that Moscovite MICA is a
very effiecient heat barrier and we now use it on all our
Tumble Stirrers that are used with heat blocks. We also use
it on the bottom of all our heat blocks as illustrated in
the photos to the right.
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Enviromental Express makes chemically-resistant graphite heat blocks called HotBlocks that can be used with our Tumble Stirrers to heat and stir caustic or corrosive chemicals. Because these chemicals can affect the Stirrer motor, Environmental Express has placed our VP 710C1 Tumble Stirrer into a protective cabinet called a StirBase. In the photo on the right, our Tumble Stirrer is located inside the lower black cabinet with the 54-Position HotBlock setting on top. The StirBase plus HotBlock combination is then used inside a fume hood.
Follow this link for more information about the StirBase.
We have also tested the Environmental Express 36-Position Manual HotBlock with our Tumble Stirrers by placing supporting legs under the HotBlock. This configuration can be used if the materials to be heated and stirred are not corrosive enough to require protection of the Tumble STirrer.
The photos to the right and videos below illustrate how a Manual HotBlock can be used with our VP 710E-2 Tumble Stirrer and our VP 710C1 Tumble Stirrer.
Download Video
(mpeg movie- 12MB)
Download Video
(mpeg movie- 11MB)
Press
the play button to view the video in a flash format, flash must
be installed, or click the download link to download a mpeg
version. |
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One of our customers wanted to get the fastest heat
transfer from our VP 741, VP 743 and VP 743A heating blocks to the wells of his deep
well microplate without using a messy liquid heat conductor. Because
most deep well microplates have a "skirt" around them, it is like having a
built in air insulator that prevents heat transfer. The
AbGene #AB-0661 with its 2.2 ml volume
and NO skirt offers a way to solve this problem. We developed a
5 piece aluminum heat insert (VP 741-I) to surround the AB-0661
plate and with the VP 741 lid, completely enclose it. The bottom
plate is machined in a sculpted fashion to closely follow the outside
contours of the plate bottom. The bottom piece fits so tight it
has to be pried off with a screwdriver. The sides and end sections are
held tight to the outside walls with a rubber band.
This is a simple yet very effective solution to enhance
heat transfer.
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The VP 741I6B is our newest aluminum heat transfer base. It was designed
specifically for the AbGene (#ab093) 96 deep well microplate. It features an sbs
footprint and is sculpted to closely follow the outside contours of the plate
bottom. It can be used on VP 741BW-R or on commercially available dry bath
heating units. Contact one of our sales staff if you require a heat transfer
base for your specific plate type.
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The VP 741I6A heating block insert is ideal for use
with the VP 741B heating block. With the "cut away" design it provides
easy access for robotic plate handlers. Made from anodized aluminum
with conical holes to match the topography of the PCR plate it provides a
very efficient transfer of heat from the heating block to the PCR
plate.
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Eddy currents are currents induced in conductors like aluminum. When a conductor is exposed to a rapidly
rotating magnetic field (present in our Tumble Stirrers) it can cause a circulating flow of electrons or current, within the body of the conductor. These circulating eddies of current
have inductance and thus induce magnetic fields. These fields can cause repulsive, attractive, propulsion and drag effects. The stronger the applied magnetic field, or the greater the
electrical conductivity of the conductor, or the faster the field changes, then the greater the currents that are developed and the greater the fields produced. In the case of Tumble
Stirrers with heat blocks and heat block inserts this produces additional heat in the block or insert and it also causes drag on the Tumble Stirrer motor.
We make specially designed inserts and heat blocks that that minimizes the Eddy current phenomena resulting from magnetic lines of flux passing through
large masses of aluminum without affecting the heat block or insert’s ability to transfer heat. Our unique Eddy current defeating design reduces the load on the magnetic stirrer's motor
and also reduces the temperature to which the aluminum insert is heated up to. This heat reduction is important in applications where the temperature of the heat insert needs to be less
than 40°C. |
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The VP 416-ALB-8 is a Heat Block Insert with SBS microplate dimensions that fits inside our standard VP 741 through VP 744 Heat Block series. It has a special
design that minimizes the Eddy current phenomena resulting from magnetic lines of flux passing through large masses of aluminum without affecting the insert’s ability to transfer
heat. The Eddy current defeating design reduces the load on the magnetic stirrer's motor and also reduces the temperature to which the aluminum insert is heated up to. This heat reduction
is important in applications where the temperature of the heat insert needs to be less than 40°C.
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The heat block insert has 8 flat bottom wells, each 25 mm in diameter. The insert comes with a lid that has holes above each well for more even heating while allowing
samples to be added or removed while the lid is still in place.
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The VP 416-ALB-20 is a heat block with
SBS microplate dimensions that fits inside
our standard VP 741 through VP 744 Heat Block series. It
has a special Eddy Current defeating
design that minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat.
The Eddy Current defeating design reduces the load on the
magnetic stirrer's motor and also reduces the temperature
that the aluminum block is heated up to. This later
phenomena in important in applications where the tempature
of the heat block needs to be less than 40°C.
The
heat block insert has 20 flat bottom wells, each 17 mm
in diameter by
20.7 mm deep.
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The vial in the
photos to the right is a
2 dram vial with dimensions
16.6 x 60 mm.
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The photo to the
right shows a structural support lid made of PEEK (VP
416-ALB-LID-1) used hold a foam silicone rubber gasket (VP
416-GASKET-1) to seal the vials in a VP 416-ALB-20 heat
block insert.. VP 416-ALB-LID-1 and VP 416-GASKET-1 are also
used to seal the vials in a VP 416_ALB-30 heat block insert.
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The VP 416-ALB-24 is a heat block with SBS microplate
dimensions insert that fits inside our standard VP 741
through VP 744 Heat Block series. It has a special Eddy
Current defeating design that minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat. The Eddy Current
defeating design reduces the load on the magnetic stirrer’s
motor and also reduces the temperature that the aluminum
block is heated up to. This latter phenomena is important in
applications where the temperature of the heat block needs
to be less than
40°C.
The
heat block insert has 24 flat
bottom wells, each
15.1 mm in
diameter by 20.7 mm deep.
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The vial in the
photos to the right is a 1 dram vial with dimensions 14.5 x 45 mm.
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The photo to the right demonstrates the
insert being used with a VP 741BW-MICA heat block and on top
of a VP 710C1 Tumble Stirrer. It also shows a heat block lid
(VP 416-ALB-LID) and a foam silicone rubber gasket (VP
416-GASKET) attached to the insert to provide a cover for
the vials. |
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The VP 416-ALB-30 is a heat block with SBS microplate
dimensions insert that fits inside our standard VP 741
through VP 744 Heat Block series. It has a special Eddy
Current defeating design that minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat. The Eddy Current
defeating design reduces the load on the magnetic stirrer’s
motor and also reduces the temperature that the aluminum
block is heated up to. This latter phenomena is important in
applications where the temperature of the heat block needs
to be less than
40°C.
The heat block insert
has 30 wells shaped to accommodate microcentrifuge
tubes.
Each well bottom has a conical shape to conform to a microcentrifuge tube and is
11 mm wide by 23.5 mm deep.
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer.
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The VP 416-ALB-48 is a heat block with SBS microplate
dimensions insert that fits inside our standard VP 741
through VP 744 Heat Block series. It has a special Eddy
Current defeating design that minimizes the eddy current
phenomena resulting from magnetic lines of flux passing
through large masses of aluminum without affecting the
insert’s ability to transfer heat. The Eddy Current
defeating design reduces the load on the magnetic stirrer’s
motor and also reduces the temperature that the aluminum
block is heated up to. This latter phenomena is important in
applications where the temperature of the heat block needs
to be less than
40°C.
The heat block insert has 48 round bottom wells
each 12 mm in diameter by
20.7 mm deep. |
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The photo to the right shows an assortment of vials, tubes,
and bottles that the
VP 416-ALB-48 will accommodate.
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer. It also shows a
VP 416-ALB-LID and
a foam silicone rubber gasket attached
to the insert to provide a cover for the vials.
The tubes used are 5 mL round bottom tubes with the dimensions
of 12 x 75 mm. |
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The VP 416-ALB-96 is a heat block
with SBS microplate dimensions insert that fits inside our
standard VP 741 through VP 744 Heat Block series. It has a
special Eddy Current defeating design that minimizes the
eddy current phenomena resulting from magnetic lines of flux
passing through large masses of aluminum without affecting
the insert’s ability to transfer heat. The Eddy Current
defeating design reduces the load on the magnetic stirrer’s
motor and also reduces the temperature that the aluminum
block is heated up to. This latter phenomena is important in
applications where the temperature of the heat block needs
to be less than
40°C.
The heat block insert has 96 flat bottom
wells each 8.6 mm
in diameter by
21.7 mm deep. |
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The vials shown in the photos to the
right have the following dimensions:
8 mm dia. x 30 mm tall
for the shorter one
8 mm dia. x 43 mm tall
for the taller one |
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The photo to the right demonstrates the insert being used
with a VP 741BW-MICA heat block and on top of a VP 710C1
Tumble Stirrer. It also shows a
VP 416-ALB-LID and
a foam silicone rubber gasket (VP
416-GASKET) attached
to the insert to provide a cover for the vials.
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The VP 416-ALB-LID and VP 416-GASKET foam silicone rubber gasket
will attach to the VP 416-ALB-24, VP
416-ALB-48 and VP 416-ALB-96 heat block inserts to provide a cover for the vials.
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The VP 744 is a
heater/chiller aluminum block with an SBS feature on the bottom so it can be
located on robot platform deck tile. Two hose barb nipples connect the
serpentine channels in the heater/chiller to a pump and a hot or cold fluid
bath. Alignment holes and or registration pins on the VP 744 allow
accessories (in this case a VP 531R-1AL aluminum reagent reservoir) to be held in the same relative position as the SBS
feature on the VP 744, thus facilitating locating the accessory relative to
the robot deck tile. If you already have hot or cold bath and a
peristaltic pump you have everything you need.
If you need a
peristaltic pump check out
VP 560. |
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The Photo to right
illustrates the serpentine heating/cooling channels. |
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The photo on the right
is a bottom view, illustrating the SBS foot print feature that registers the
heating block to most robot plate tiles.
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The photo on the right
illustrates a VP 531R-1AL on the heating/chilling block.
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The VP 744A is a heater/chiller device which when connected to recirculating
water bath can regulate the temperature of a microplate. The bottom portion of
the VP 744A has the same SBS dimensions as a Microplate so it will fit into a
robot deck tile and the top of the VP 744A will accommodate a Microplate.
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The photos to the right illustrate the VP 744A on a VP 710G6 Tumble Stirrer, a
V&P Pin Tool Robot deck and a Mini-Trak deck. With its open architecture,
the VP 744A is well suited for robotic work station applications as it is
easy for plate handlers to pick up and deliver microplates to the device.
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Specifications:
Overall
Length = 5.420"
Width = 4.134"
Height = 1.375"
SBS Footprint
Length = 5.020"
Width = 3.355"
Height = 0.50" |
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The VP 744B-MB was designed to be used to heat or chill deep or standard well
microplates. The VP 744B-MB also comes equipped with a screw down lid that can be
used to seal the wells. Simply connect the nipples to any recirculating bath. In addition, the VP 744B-MB is designed to minimize Eddy Current drag.
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The VP 744B-MB also has VP 581BMICA on the bottom to allow it to placed and
located on deck tiles.
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VP 745 Heater/Chiller block for regulating the temperature of a VP
750 Bubble Paddle Stirrer. We designed this system to fit on the deck
of a Caliper Sciclone with a VP 710C1 under the deck to power the Bubble
Paddle Stirrer. Just attach to a heater/chiller bath and a pump.
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Aluminum microplate to keep liquid in
wells cool. |
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The VP 581C-AL was designed to keep the
contents of a microplate cool while on a robotic work
station. Made from block of solid aluminum 2.54 cm
thick the
VP 581C-AL will keep a microplate between 7C and
10C for over 15 minutes.
Follow this link to data showing the
ability of the VP 581C-AL to stabilize the temperature of a
96 well microplate with 300 ul of distilled water in each
well. The VP 581C-AL were either chilled to 7.8C or
-13C prior to placing on the robot deck. |
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Another more cost effective way to automate any of our
Heating Blocks is to use our new Programmable Smart Switch VP 700.
Follow
this link for more information.
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We also make custom inserts for heating blocks. The
one at the right was machined so the inside of the hole matched perfectly
with the round bottom of each of the different containers. The one
below incorporates various diameter holes and bottoms that conform very
closely with the outside surface of the glass bottles they hold. The
circular design facilitates stirring on a conventional horizontal magnetic
stirrer.
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